

<!-- RR Donnelley Xcelerate Taxonomy Schema, based on XBRL 2.1  http://www.rrdonnelley.com/ -->
<!-- Version: 6.22.4 -->
<!-- Round: 4 -->
<!-- Creation date: 2015-08-07T04:18:24Z -->
<!-- Copyright (c) 2005-2013 R.R. Donnelley & Sons Company All Rights Reserved. -->
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        <link:definition>125 - Disclosure - Property and Equipment, net (Tables)</link:definition>
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        <link:definition>133 - Disclosure - Net Income Per Common Share - Additional Information (Detail)</link:definition>
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        <link:definition>135 - Disclosure - Property and Equipment, net - Summary of Property and Equipment, Net (Detail)</link:definition>
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        <link:definition>136 - Disclosure - Commitments and Contingencies - Future Minimum Lease Payments under Operating Leases (Detail)</link:definition>
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        <link:definition>137 - Disclosure - Commitments and Contingencies - Additional Information (Detail)</link:definition>
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        <link:definition>138 - Disclosure - Share-Based Compensation - Additional Information (Detail)</link:definition>
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        <link:definition>139 - Disclosure - Share-Based Compensation - Summary of Activity Related to Restricted Stock Granted under Incentive Plan (Detail)</link:definition>
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        <link:definition>140 - Disclosure - Share-Based Compensation - Summary of Activity Related to Stock Options Granted under Company's Incentive Plan (Detail)</link:definition>
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        <link:definition>141 - Disclosure - Share-Based Compensation - Summary of Activity Related to Stock Options Granted under Company's Incentive Plan (Parenthetical) (Detail)</link:definition>
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        <link:definition>142 - Disclosure - Share-Based Compensation - Share-Based Compensation Expense (Detail)</link:definition>
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        <link:definition>143 - Disclosure - Treasury Stock - Additional Information (Detail)</link:definition>
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  <import namespace="http://xbrl.sec.gov/sic/2011-01-31" schemaLocation="http://xbrl.sec.gov/sic/2011/sic-2011-01-31.xsd"/>
  <import namespace="http://xbrl.sec.gov/stpr/2011-01-31" schemaLocation="http://xbrl.sec.gov/stpr/2011/stpr-2011-01-31.xsd"/>
  <element name="AdmissionAdvisoryAndRelatedExpensesPolicyPolicyTextBlock" id="lope_AdmissionAdvisoryAndRelatedExpensesPolicyPolicyTextBlock" type="nonnum:textBlockItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item"/>
  <element name="AdmissionsAdvisoryAndRelatedExpenses" id="lope_AdmissionsAdvisoryAndRelatedExpenses" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item"/>
  <element name="AdvisoryServicesMember" id="lope_AdvisoryServicesMember" type="nonnum:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item"/>
  <element name="AssetsAcquiredByCapitalLease" id="lope_AssetsAcquiredByCapitalLease" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item"/>
  <element name="CashAndCashEquivalentMaturityPeriod" id="lope_CashAndCashEquivalentMaturityPeriod" type="xbrli:durationItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item"/>
  <element name="DateForReleasingPenaltyFundsAndInterestToUniversity" id="lope_DateForReleasingPenaltyFundsAndInterestToUniversity" type="xbrli:dateItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item"/>
  <element name="DefaultAmountOfLatePaymentPenaltyUnderDispute" id="lope_DefaultAmountOfLatePaymentPenaltyUnderDispute" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="instant" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item"/>
  <element name="DocumentAndEntityInformationAbstract" id="lope_DocumentAndEntityInformationAbstract" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item"/>
  <element name="ExpirationDateOnRepurchaseAuthorizations" id="lope_ExpirationDateOnRepurchaseAuthorizations" type="xbrli:dateItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item"/>
  <element name="FixedRateOfInterestOnLoans" id="lope_FixedRateOfInterestOnLoans" type="num:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item"/>
  <element name="IncreaseDecreaseInDeferredRent" id="lope_IncreaseDecreaseInDeferredRent" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item"/>
  <element name="InstructionalCostsAndServices" id="lope_InstructionalCostsAndServices" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item"/>
  <element name="InstructionalCostsAndServicesMember" id="lope_InstructionalCostsAndServicesMember" type="nonnum:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item"/>
  <element name="InterestExpenseOnDerivativesRelatedToCreditRisk" id="lope_InterestExpenseOnDerivativesRelatedToCreditRisk" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item"/>
  <element name="InterestRateCorridorMember" id="lope_InterestRateCorridorMember" type="nonnum:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item"/>
  <element name="InvestmentMaturityPeriod" id="lope_InvestmentMaturityPeriod" type="xbrli:stringItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item"/>
  <element name="MarketingAndPromotionalPolicyPolicyTextBlock" id="lope_MarketingAndPromotionalPolicyPolicyTextBlock" type="nonnum:textBlockItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item"/>
  <element name="MaximumPercentageOfVariableInterestRatesBasedOnBaseInterestRate" id="lope_MaximumPercentageOfVariableInterestRatesBasedOnBaseInterestRate" type="num:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item"/>
  <element name="NonemployeeMember" id="lope_NonemployeeMember" type="nonnum:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item"/>
  <element name="NotesReceivableInterestRate" id="lope_NotesReceivableInterestRate" type="num:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item"/>
  <element name="NotesReceivablePolicyTextBlock" id="lope_NotesReceivablePolicyTextBlock" type="nonnum:textBlockItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item"/>
  <element name="NumberOfAnniversariesOfGrantDateUponWhichRestrictedStockUnitsVest" id="lope_NumberOfAnniversariesOfGrantDateUponWhichRestrictedStockUnitsVest" type="xbrli:positiveIntegerItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item"/>
  <element name="NumberOfColleges" id="lope_NumberOfColleges" type="xbrli:integerItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item"/>
  <element name="NumberOfDegreeProgramsOffered" id="lope_NumberOfDegreeProgramsOffered" type="xbrli:integerItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item"/>
  <element name="PercentageDeductedFromBaseInterestRateForActualPayment" id="lope_PercentageDeductedFromBaseInterestRateForActualPayment" type="num:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item"/>
  <element name="PercentageOfAmountPaidByUniversity" id="lope_PercentageOfAmountPaidByUniversity" type="num:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item"/>
  <element name="PeriodForWriteOffInactiveStudentAccounts" id="lope_PeriodForWriteOffInactiveStudentAccounts" type="xbrli:durationItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item"/>
  <element name="PeriodOfBaseInterestRate" id="lope_PeriodOfBaseInterestRate" type="xbrli:durationItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item"/>
  <element name="PrepaidRoyaltiesNoncurrent" id="lope_PrepaidRoyaltiesNoncurrent" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="instant" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item"/>
  <element name="PurchasesOfPropertyAndEquipmentIncludedInAccountsPayable" id="lope_PurchasesOfPropertyAndEquipmentIncludedInAccountsPayable" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item"/>
  <element name="RealEstatePropertyDescription" id="lope_RealEstatePropertyDescription" type="xbrli:stringItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item"/>
  <element name="ReductionInRevenueDueToScholarshipsOfferedToStudents" id="lope_ReductionInRevenueDueToScholarshipsOfferedToStudents" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item"/>
  <element name="RegulatoryTextBlock" id="lope_RegulatoryTextBlock" type="nonnum:textBlockItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item"/>
  <element name="ShortfallTaxExpenseFromShareBasedCompensation" id="lope_ShortfallTaxExpenseFromShareBasedCompensation" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item"/>
  <element name="SinceApprovalOfShareRepurchasePlanMember" id="lope_SinceApprovalOfShareRepurchasePlanMember" type="nonnum:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item"/>
  <element name="StatutoryTrusteeFeeDueAmountUnderDispute" id="lope_StatutoryTrusteeFeeDueAmountUnderDispute" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="instant" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item"/>
  <element name="StockholdersEquityLineItems" id="lope_StockholdersEquityLineItems" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item"/>
  <element name="StockholdersEquityTable" id="lope_StockholdersEquityTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem"/>
  <element name="StockOptionAndRestrictedStockAwardsMember" id="lope_StockOptionAndRestrictedStockAwardsMember" type="nonnum:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item"/>
  <element name="SummaryOfSignificantAccountingPoliciesLineItems" id="lope_SummaryOfSignificantAccountingPoliciesLineItems" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item"/>
  <element name="SummaryOfSignificantAccountingPoliciesTable" id="lope_SummaryOfSignificantAccountingPoliciesTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem"/>
  <element name="TaxBenefitOfSpiritWarrantIntangible" id="lope_TaxBenefitOfSpiritWarrantIntangible" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item"/>
  <element name="UnauditedInterimFinancialInformationPolicyTextBlock" id="lope_UnauditedInterimFinancialInformationPolicyTextBlock" type="nonnum:textBlockItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item"/>
</schema>





